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A conserved AAA+ ATPase, called Cdc48 in yeast and p97 or VCP in metazoans, plays an off white 5000 puffs essential role in many cellular processes by segregating polyubiquitinated proteins from complexes or membranes.For example, in endoplasmic reticulum (ER)-associated protein degradation (ERAD), Cdc48/p97 pulls polyubiquitinated, misfolded prote
The educational act is a complex process.Teaching is an art.Even at present time, most classes off white 5000 puffs in different institutions, schools, high schools or universities, are orthodox lectures that make the students lose their interest for learning.Pedagogical mediation is a valuable instrument that should be applied by most educators so